#

We specialise in the development of bespoke, automated analysis pipelines that are tailoured for your requirements.

Social media:

Share this page:

Get in touch

Contact Us

What we do

We know why you're here: you're struggling with some data and need a helping hand. We're happy to assist and will speak to you at whatever level you're at, and in the process show you the methods that we use so that you can also learn the tools of the trade and become you're own analyst.

We know the different types of pressures that are felt by private, clinical, and academic personnel - we've felt them ourselves in our careers.

What follows is a hint of what we do, to give you an idea.


Data analysis
  • Next generation sequencing (NGS):  DNA-seq, RNA-seq, ChIP-seq
  • Whole genome sequencing and exome sequencing
  • DNA microarrays and cDNA microarrays
  • Fluidigm
  • NanoString
  • Mass cytometry / CyTOF
  • Mass spectrometry
  • Metabolomics
  • De novo transcriptome assembly
  • Fusion gene search
  • Non-coding RNA (ncRNA) (including lincRNA and antisense transcripts)
  • GWAS (genome-wide association studies)
  • Copy number variation (CNV)
  • Networks, graphs, and minimal spanning trees
Copy number variation (CNV)
Biostatistics
  • Linear and logistic regression models
  • Bayesian regression models
  • Lasso, ridge, and elastic net penalised regression
  • Cross-validation
  • Biomarker identification and risk model development
  • Gap statistic
  • Correlation analysis
  • Clustering analysis (k-means, partitioning around medoids (PAM), hierarchical, et cetera)
  • ROC analysis
  • Principal components analysis (PCA) / Linear discriminant analysis (LDA)
  • Eigenvector and eigenvalue classification
Circos plot and clustering with compex heatmap
Training material / Workshops
  • Introduction to bioinformatics 2-day workshop
  • R Programming Language - extremely broad and includes topics as simple as basic statistics and as advanced as microarray analysis
  • Clinical genetics - everything that you need to know about NGS in the clinical diagnostic setting (focused on UK regulations and recommendations)
  • Introduction to UNIX and Linux
  • Next generation sequencing (NGS) analysis
  • Networks, graphs, and spanning trees
Clinical next generation sequencing (NGS) pipeline
Data mining
  • ClinVar
  • 1000 Genomes
  • International HapMap
  • GME (Greater Middle East)
  • COSMIC (Catalogue of Somatic Mutations in Cancer)
  • DAVID (Database for Annotation, Visualization, and Integrated Discovery)
  • dbSNP (Single Nucleotide Polymorphism database)
  • DGV (Database of Genomic Variants)
  • GO (Gene Ontology)
  • HGVS (Human Genome Variation Society)
  • HUGO (Human Genome Organisation)
  • KEGG (Kyoto Encyclopedia of Genes and Genomes)
  • NCBI (National Centre for Biotechnology Information)
  • TCGA (The Cancer Genome Atlas)
  • UCSC Genome Bioinformatics
  • UniProtKB/Swiss-Prot
Data mining